Half Life and Dose of Medicines

October 14, 2020 | by pkmedics

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List of Half Life and Dose of Tablets

CALCIUM CHANNEL BLOCKERS

BRAND NAME	GENERIC NAME	HALF LIFE	DOSE
NORVASC TAB 5mg & 10 mg	AMLODIPINE	25-30 hrs	OD
ADALAT TAB 30mg & 60 mg	NIFEDIPINE	1.5-3 hrs	TDS
CALAN TAB 40mg & 80 mg	VERAPAMIL	2.5-8 hrs	OD-BID
HERBESSER TAB 90mg &180mg SR	DILTIAZEM	3-4.5 hrs	BID- TDS

ARB’s (Angiotensin Receptor Blockers)

BRAND NAME	GENERIC NAME	HALF LIFE	DOSE
NUVAL TAB 80 mg & 160 mg	VALSARTAN	6 hrs	OD-BD
COVA TAB 80 mg & 160 mg	VALSARTAN	6 hrs	OD
DIOVAN TAB 80 mg & 160 mg	VALSARTAN	6-9 hrs	OD
ADVANT T AB 8mg & 16 mg	CANDESARTAN CILEXETIL	9 hrs	OD-BID
EZIDAY TAB 25mg & 50 mg	LOSARTAN POTASSIUM	6-9 hrs	BID
MISAR TAB 20mg & 40mg & 80mg	TELMISARTAN	15-20 hrs	OD

doctor giving pills to client in clinic — https://pksurigical.com/half-life-and-dose-of-medicines/

ARB’s COMBINATION

BRAND NAME	GENERIC NAME	HALF LIFE	DOSE
CO-EZIDAY TAB 50/12.5 &100/25mg	LOSARTAN POTASSIUM+HYDROCHLOROTHIAZIDE	6-9hrs	OD
COVAM TAB 5/80, 5/160, 10/160 mg	AMLODIPINE+VALSARTAN	6-8 hrs	OD
AV- SARTAN TAB 5/80, 5/160, 10/160 mg	AMLODIPINE+VALASRTAN	6-8 hrs	OD
NEW DAY TAB 5/80, 5/160, 10/160 mg	AMLODIPINE+VALSARTAN	6-8 hrs	OD
EXFORAGE TAB 5/80, 5/160, 10/160 mg	AMLODIPINE+VALSARTAN	6 hrs	OD
COVA –H TAB 80/12.5, 160/12.5 mg	VALSARTAN+HYDROCHLOROTHIAZIDE	6 hrs	OD
CO-DIOVAN TAB 80/12.5, 160/12.5, 160/25 mg	VALSARTAN+HYDROCHLOROTHIAZIDE	6 hrs	OD

HALF LIFE AND DOSE OF B- BLOCKERS

BRAND NAME	GENERIC NAME	HALF LIFE	DOSE
CARSEL TAB 25mg & 50mg & 100 mg	METOPROLOL TARTRATE	3-6 hrs	BD
MEPRESSOR TAB 100mg	METOPROLOL TARTRATE	3-6 hrs	BID- TDS
INDERAL TAB 10mg & 40mg	PROPRANOLOL HYDROCHLORIDE	3-6 hrs	BD
TENORMIN TAB 25mg & 50mg & 100mg	ATENOLOL	6 hrs	OD-BID
BLOKIUM TAB 50mg & 100mg	ATENOLOL	6 hrs	OD-BID
VEDICAR TAB 6.25mg & 12.5mg & 25mg	CARVEDILOL	6-10 hrs	OD –BID
NEBIX TAB 2.5mg & 5mg	NEBIVOLOL	9-12 hrs	OD-BID
MONITOR TAB 2.5mg, 5mg, 10mg	BISOPROLOL FUMARATE	10-12 hrs	OD -BID
CONCOR TAB 2.5mg, 5mg, 10mg	BISOPROLOL FUMARATE	10-12 hrs	OD -BID

ACE INHIBITORS

BRAND NAME	GENERIC NAME	HALF LIFE	DOSE
RAMIPACE TAB 1.25, 2.5, 5, 10mg	RAMIPRIL	5-6 hrs	OD-BD
CORACE5 TAB 5mg & 10 mg	LISINOPRIL	12 hrs	OD
CARDIOTEC TAB 5mg & 10 mg	ENALAPRIL MALEATE	4-6 hrs	OD-BID
CO-CARDIOTEC TAB 10/25mg	ENALAPRIL MALEATE + HYDROCHOLOROTHIAZIDE	5-14 hrs	OD
CAPOTEN TAB 25mg & 50mg	CAPTOPRIL	1-2 hrs	BID

ANTI ANGINAL

BRAND NAME	GENERIC NAME	HALF LIFE	DOSE
NIGLYS TAB 2.6mg & 6.4mg	GLYCERYL TRINITRATE	6-8 hrs	BD
NITROMINT TAB 2.6mg & 6.5mg	NITROGLYCERINE	6-8 hrs	BID
CARDNIT TAB 2.6m & 6.4 mg	GLYCERYL TRINITRATE	6-8 hrs	BID
SUSTAC TAB 2.6m & 6.4 mg	GLYCERYL TRINITRATE	4-5 hrs	BID
VASTAREL-MR TAB 35mg	TRIMETAZIDINE DI-HYDROCHOLORIDE	5-6 hrs	BD
IVATAB/CORALAN TAB 5mg & 7.5 mg	IVABRADINE	2-11 hrs	OD-BID
RANOLA TAB 1000mg & 500 mg	RANOLAZINE	7 hrs	OD-BID

LIPID LOWERING DRUGS

BRAND NAME	GENERIC NAME	HALF LIFE	DOSE
LIPIREX TAB 10, 20 & 40mg	ATORVASTATIN	14 hrs	HS
LIPIGET TAB 10, 20 & 40mg	ATORVASTATIN	14 hrs	HS
LIPITOR TAB 10, 20 & 40mg	ATORVASTATIN	14 hrs	HS
X-PLENDED TAB 5,10 & 20mg	ROSUVASTATIN	19 hrs	HS
ROLIP TAB 5,10 & 20mg	ROSUVASTATIN	19 hrs	HS
SURVIVE TAB 10, 20 & 40mg	SIMVASTATIN	2-5 hrs	OD-BID
GEMPID TAB 600 mg	GEMFIBROZIL	1.5 hrs	BID
PITALO TAB 1, 2 & 4 mg	PITAVASTATIN	12 hrs	OD

PROTON PUMP INHIBITORS

BRAND NAME	GENERIC NAME	HALF LIFE	DOSE
MEPRAZOLE CAP 20mg & 40mg	OMEPRAZOLE	0.5-3hrs	OD
RISEK CAP 20mg & 40mg	OMEPRAZOLE	0.5-3 hrs	OD
OMEGA CAP 20mg & 40mg	OMEPRAZOLE	0.5-3 hrs	OD
NEXUM CAP 20mg & 40mg	ESOMEPRAZOLE	1-1.5 hrs	BID
ZOPENT CAP 20mg & 40mg	PANTOPRAZOLE	2 hrs	BID

DIURETICS

BRAND NAME	GENERIC NAME	HALF LIFE	DOSE
LASIX TAB 20mg & 40mg	FUROSEMIDE	9 hrs	OD-BID
SPIROMIDE TAB 20mg & 40mg	FUROSEMIDE+SPIRONOLACTONE	9-10 hrs	OD-BID
ALDACTONE TAB 25mg & 50mg	SPIRONOLACTONE	30.5 hrs	OD
LASORIDE TAB 40mg	FUROSEMIDE+AMILORIDE HCL	6-9 hrs	BID

ANTI ARRHYTHMIC/ K+CHANNEL BLOCKER

BRAND NAME	GENERIC NAME	HALF LIFE	DOSE
MIODARONE TAB 200mg	AMIDARONE HCL	24 hrs	OD
CORDARONE TAB 100mg & 200MG	AMIDARONE HCL	24 hrs	OD

ANTI DIABETICS

BRAND NAME	GENERIC NAME	HALF LIFE	DOSE
GETRYL TAB 1, 2, 3 & 4mg	GLIMEPIRIDE	5 hrs	BID
DIABOLD TAB 1, 2, 3 & 4mg	GLIMIPIRIDE	5 hrs	BID
DAONIL TAB 5mg	GLIBENCLAMIDE	5 hrs	BID
GLUCOPHAGE TAB 500,850 & 1000mg	METFORMIN	6 hrs	BID
DIAMICRON MR TAB 30	GLICLAZIDE	4-6hrs	BID

H2 RECEPTOR BLOCKER

BRAND NAME	GENERIC NAME	HALF LIFE	DOSE
ULCENIL TAB 20mg & 40mg	FAMOTIDINE	2.5-3.5 hrs	OD

ANTI PLATELETS

BRAND NAME	GENERIC NAME	HALF LIFE	DOSE
LOWPLATE TAB 75 mg & 300mg	CLOPIDOGREL	7-8 hrs	OD
LOWPLATE PLUS TAB 75 mg	ASPIRIN +CLOPIDOGREL	8 hrs	OD
LOPRIN TAB 75mg & 150mg	ASPIRIN	15 mins-3 hrs	OD

ANTI COAGULANTS

BRAND NAME	GENERIC NAME	HALF LIFE	DOSE
WARFARIN TAB 5 mg	WARFIN	20-60 hrs	OD
X-CEPT TAB 10-15-20 mg	RIVAROXABAN	18 hrs	OD

BENZODIAZEPENES

BRAND NAME	GENERIC NAME	HALF LIFE	DOSE
NERVIN TAB 0.25mg & 0.5 mg	ALPROZOLAM	11.2 hrs	OD
CITANEW TAB 5, 10 & 20mg	ESCITALOPRAM	27-33 hrs	OD
SAKOON TAB 3 mg	BROMAZEPAM	17 hrs	OD
LEXOTANIL TAB 3mg	BROMAZEPAM	17 hrs	OD

POTASSIUM CHANNEL ACTIVATOR

BRAND NAME	GENERIC NAME	HALF LIFE	DOSE
IKODIL TAB 10mg & 20mg	NICORANDIL	1hr	BID

ANTI BIOTICS

BRAND NAME	GENERIC NAME	HALF LIFE	DOSE
LEFLOX TAB 25mg & 500 mg	LEVOFLAXACIN	6-8 hrs	OD-BD
MOXIGET TAB 400mg	MOXIFLOXACIAN	11.5-15.6 hrs	OD
AZOMAX TAB 250mg & 500mg	AZITHROMYCIN	11 hrs	OD
KLARICID TAB 250mg & 500 mg	CLARITHROMYCIN	3-9 hrs	BID
CIPRIN TAB 250mg & 500 mg	CIPROFLOXACIN	2-5 hrs	BID
AUGMENTIN TAB 375, 625 & 1000mg	CO-AMOXICLAV	2-4 hrs	BID

NSAID’s

ANSAID TAB 100mg	FLURBIPROFEN	4-7 hrs	OD-BD
PONSTAN TAB 250mg & 500mg	MEFENAMIC ACID	2-4 hrs	TDS
PARACETAMOL 500mg	PANADOL	1-3 hrs	BID
NUBEROL FORTE TAB	PARACETAMOL+ORPHINIDERINE	13-20 hrs	OD
DIAGESIC-P TAB	PARACETAMOL+CAFFIENE+THIORIDAZINE	3-5 hrs	BID

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